The Top Ranked Football Players of All-Time from South Carolina High Schools Help Keep the Site Ad Free By Supporting us at Patreon
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The Top Ranked Football Players of All-Time from South Carolina High Schools
Notes: This is a list of the greatest pro players who finished high school in this state.
What players did in high school or college does not factor into this list.
| High School | Athlete | POS | Rookie | Rnk |
| Abbeville (Abbeville) | Leomont Evans | DB | 1996 | 18287 |
| Abbeville (Abbeville) | Charlie Timmons | RB | 1942 | 22697 |
| Abbeville (Abbeville) | Kennan Gilchrist | LB | 2017 | 31961 |
| Aiken (Aiken) | William Perry | DL | 1985 | 3769 |
| Aiken (Aiken) | Terrance Smith | LB | 2010 | 22377 |
| Aiken (Aiken) | Jamal Reynolds | DL | 2001 | 27508 |
| Airport (West Columbia) | Duce Staley | RB | 1997 | 2080 |
| Airport (West Columbia) | Jim Stuckey | DL | 1980 | 6429 |
| Airport (West Columbia) | Duce Staley (KR) | KR | 1997 | 12971 |
| Airport (West Columbia) | Paxton Brooks | P | 2023 | 38072 |
| Allendale-Fairfax (Allendale) | Bashaud Breeland | DB | 2014 | 4542 |
| Allendale-Fairfax (Allendale) | Bashaud Breeland (KR) | KR | 2014 | 15929 |
| Allendale-Fairfax (Fairfax) | Kenny Harney | LB | 2002 | 29599 |
| Aynor (Aynor) | T.J. Johnson | OL | 2013 | 24807 |
| Bamberg-Ehrhardt (Bamberg) | A.J. Cann | OL | 2015 | 5673 |
| Bamberg-Ehrhardt (Bamberg) | Da'Quan Bowers | DL | 2011 | 18994 |
| Bamberg-Ehrhardt (Bamberg) | Ricky Sapp | LB | 2010 | 28572 |
| Barnwell (Barnwell) | Marcus McKethan | OL | 2022 | 27936 |
| Barnwell (Barnwell) | Henry Taylor | DL | 1998 | 28821 |
| Barr St. (Lancaster) | Jim H. Duncan | DL | 1950 | 6322 |
| Barr St. (Lancaster) | Bill Belk | DL | 1968 | 6455 |
| Batesburg-Leesville (Batesburg) | Ed McDaniel | LB | 1992 | 1919 |
| Batesburg-Leesville (Batesburg) | Dontrelle Inman | WR | 2011 | 7078 |
| Battery Creek (Beaufort) | Greg Jones | RB | 2004 | 4891 |
| Battery Creek (Beaufort) | James Saxon | RB | 1988 | 5796 |
| Battery Creek (Beaufort) | Oliver Quass | K | 1996 | 32487 |
| Battery Creek (Beaufort) | Collin Drafts | QB | 2007 | 35262 |
| Beaufort (Beaufort) | Ron Parker | DB | 2011 | 6304 |
| Beaufort (Beaufort) | Boyce Green | RB | 1983 | 8273 |
| Beaufort (Beaufort) | Boyce Green (KR) | KR | 1983 | 15543 |
| Beaufort (Beaufort) | Devin Taylor | DL | 2013 | 16261 |
| Beaufort (Beaufort) | Ryan Cave | OL | 2010 | 28399 |
| Bennettsville (Bennettsville) | Syvelle Newton | WR | 2007 | 35671 |
| Berea (Greenville) | Jermale Kelly | WR | 2001 | 31178 |
| Berkeley (Moncks Corner) | Andre Ellington | RB | 2013 | 5464 |
| Berkeley (Moncks Corner) | Clarence Williams | RB | 1977 | 7634 |
| Berkeley (Moncks Corner) | Bruce Ellington (KR) | KR | 2014 | 10766 |
| Berkeley (Moncks Corner) | Bruce Ellington (PR) | PR | 2014 | 12058 |
| Berkeley (Moncks Corner) | Bruce Ellington | WR | 2014 | 13863 |
| Berkeley (Moncks Corner) | Clarence Williams (KR) | KR | 1977 | 15690 |
| Berkeley (Moncks Corner) | Andre Ellington (KR) | KR | 2013 | 16184 |
| Berkeley (Moncks Corner) | Mike Dingle | RB | 1991 | 25657 |
| Berkeley (Moncks Corner) | Ryan Stewart | DB | 1996 | 26352 |
| Berkeley (Moncks Corner) | Jabari Levey | OL | 2006 | 31546 |
| Berkeley (Moncks Corner) | Alex Taylor (OL) | OL | 2020 | 37392 |
| Bishop England (Charleston) | Derek Hughes | RB | 1982 | 36729 |
| Bishopville (Bishopville) | Corey Peoples | DB | 2005 | 29592 |
| Blythewood (Blythewood) | Justin Bethel | DB | 2012 | 14002 |
| Boiling Springs (Boiling Springs) | Storm Duck | DB | 2024 | 29346 |
| Boiling Springs (Boiling Springs) | NaJee Thompson | DB | 2023 | 37838 |
| Bonds-Wilson (North Charleston) | Art Shell | OL | 1968 | 164 |
| Bonds-Wilson (North Charleston) | Dave Meggett (PR) | PR | 1989 | 2232 |
| Bonds-Wilson (North Charleston) | Dave Meggett | RB | 1989 | 2937 |
| Bonds-Wilson (North Charleston) | Dave Meggett (KR) | KR | 1989 | 3219 |
| Bonds-Wilson (North Charleston) | Jim Johnson | DB | 1968 | 24135 |
| Boys (Anderson) | Bob Gage (PR) | PR | 1949 | 10075 |
| Boys (Anderson) | Bob Gage | RB | 1949 | 10871 |
| Brewer (Greenwood) | John Gilliam | WR | 1967 | 255 |
| Brewer (Greenwood) | John Gilliam (KR) | KR | 1967 | 8789 |
| Brewer (Greenwood) | John Gilliam (PR) | PR | 1967 | 15960 |
| Brewer (Greenwood) | Bill Wideman | DL | 1973 | 31021 |
| Brookland-Cayce (Cayce) | Dakota Dozier | OL | 2014 | 19384 |
| Brookland-Cayce (Cayce) | John Cagle | DL | 1969 | 25093 |
| Broome (Spartanburg) | Gabe Wilkins | DL | 1994 | 10044 |
| Broome (Spartanburg) | D.J. Moore (DB) | DB | 2009 | 19375 |
| Broome (Spartanburg) | D'Marco Jackson | LB | 2022 | 26393 |
| Broome (Spartanburg) | Mike Reid (DB) | DB | 1993 | 35135 |
| Burke (Charleston) | Malcolm Barnwell | WR | 1980 | 6727 |
| Burke (Charleston) | Zola Davis | WR | 1999 | 26855 |
| Burke (Charleston) | Fadol Brown | DL | 2017 | 28564 |
| Burke (Charleston) | Ray Green | DB | 2000 | 30591 |
| Burks (Charleston) | Oronde Gadsden | WR | 1995 | 6160 |
| Butler (Hartsville) | Rufus Bess | DB | 1979 | 7839 |
| Butler (Hartsville) | Rufus Bess (PR) | PR | 1979 | 12593 |
| Butler (Hartsville) | Rufus Bess (KR) | KR | 1979 | 12812 |
| Byrnes (Duncan) | Steve Durham | DL | 1982 | 25009 |
| Byrnes (Duncan) | Ben Hall | TE | 2005 | 31217 |
| Byrnes (Duncan) | Noah Dawkins | LB | 2019 | 31640 |
| Byrnes (Duncan) | Bradley Robinson | DB | 2008 | 33391 |
| Byrnes (Duncan) | Prince Miller | DB | 2010 | 34622 |
| Cainhoy (Huger) | Robert Porcher | DL | 1992 | 801 |
| Cainhoy (Huger) | Luther Broughton | TE | 1998 | 10293 |
| Calhon County (St. Matthews) | Alshon Jeffery | WR | 2012 | 1732 |
| Calhoun County (St. Matthews) | DeAngelo Willingham | DB | 2009 | 31539 |
| Calhoun County (St. Matthews) | Alonzo Shuler | DL | 2003 | 33999 |
| Camden (Camden) | Bobby Engram | WR | 1996 | 2302 |
| Camden (Camden) | Vonnie Holliday | DL | 1998 | 2693 |
| Camden (Camden) | Bobby Engram (PR) | PR | 1996 | 7177 |
| Camden (Camden) | Bobby Engram (KR) | KR | 1996 | 14592 |
| Carolina Academy (Greenville) | Corey Louchiey | OL | 1994 | 22225 |
| Carolina Academy (Greenville) | Devaroe Lawrence | DL | 2017 | 25617 |
| Carver (Spartanburg) | Howie Williams | DB | 1962 | 5855 |
| Carver (Spartanburg) | Harris Jones | OL | 1971 | 23010 |
| Carvers Bay (Hemingway) | Robert Geathers | DL | 2004 | 4692 |
| Carvers Bay (Hemingway) | Byron Young (LB) | LB | 2023 | 10301 |
| Carvers Bay (Hemingway) | Clayton Geathers | DB | 2015 | 21432 |
| Carvers Bay (Hemingway) | Clifton Geathers | DL | 2010 | 26203 |
| Carvers Bay (Hemingway) | Kwame Geathers | DL | 2013 | 34614 |
| Carvers Bay (Hemingway) | Donovan Richard | DB | 2013 | 37404 |
| Central (Fairfield) | Mike Anderson | RB | 2000 | 3040 |
| Central (Pageland) | Corey Miller | LB | 1991 | 4631 |
| Central (Pageland) | Fletcher Louallen | DB | 1984 | 24130 |
| Chapman (Inman) | Deebo Samuel | WR | 2019 | 1936 |
| Chapman (Inman) | Deebo Samuel (KR) | KR | 2019 | 13527 |
| Chapman (Inman) | Jermaine Petty | LB | 2002 | 32373 |
| Chapman (Inman) | Toby Cates | WR | 1995 | 37647 |
| Charleston (Charleston) | Clay Matthews Sr. | DL | 1950 | 6478 |
| Charleston (Charleston) | Julian Nunamaker | DL | 1969 | 20412 |
| Cheraw (Cheraw) | Harry Newsome | P | 1985 | 2251 |
| Cheraw (Cheraw) | Dale Hatcher | P | 1985 | 3611 |
| Cheraw (Cheraw) | Jaron Brown | WR | 2013 | 6355 |
| Cheraw (Cheraw) | Cliff Matthews | DL | 2011 | 26307 |
| Cheraw (Cheraw) | Andy Hall | QB | 2004 | 32468 |
| Chester (Chester) | Marion Campbell | DL | 1952 | 1637 |
| Chester (Chester) | Maurice Morris | RB | 2002 | 3012 |
| Chester (Chester) | Maurice Morris (KR) | KR | 2002 | 9348 |
| Chester (Chester) | Ken Callicutt (KR) | KR | 1978 | 13491 |
| Chester (Chester) | Maurice Morris (PR) | PR | 2002 | 16797 |
| Chester (Chester) | Ken Callicutt | RB | 1978 | 18833 |
| Chicora (Charleston) | Jim David | DB | 1952 | 899 |
| Choppee (Georgetown) | Jumpy Geathers | DL | 1984 | 5600 |
| Choppee (Georgetown) | Ervin Parker | LB | 1980 | 11940 |
| Choppee (Georgetown) | Lorenzo Bromell | DL | 1998 | 21314 |
| Choppee (Georgetown) | Lamont Bryant | DL | 2001 | 26788 |
| Christ Church Episcopal (Greenville) | Chandler Catanzaro | K | 2014 | 6282 |
| Clinton (Clinton) | Kevin Long | RB | 1977 | 3096 |
| Clover (Clover) | Lamont Hall | TE | 1998 | 10892 |
| Clover (Clover) | Nick Sciba | K | 2022 | 38041 |
| Colleton County (Walterboro) | Norman Hand | DL | 1995 | 6198 |
| Colleton County (Walterboro) | Eric Stephens | DB | 1994 | 30294 |
| Colleton County (Walterboro) | Ron Maree | OL | 1971 | 31058 |
| Columbia (Columbia) | Angelo King | LB | 1981 | 11360 |
| Columbia (Columbia) | Ventrell Jenkins | DL | 2011 | 31152 |
| Columbus (Lake View) | Charlie Bryant (KR) | KR | 1966 | 12888 |
| Columbus (Lake View) | Charlie Bryant | RB | 1966 | 19541 |
| Comprehensive (York) | Spencer Lanning | P | 2011 | 17855 |
| Conway (Conway) | Bryan Edwards | WR | 2020 | 17513 |
| Conway (Conway) | Junior Hemingway | WR | 2012 | 19279 |
| Conway (Conway) | George Gause | DL | 2005 | 28430 |
| Conway (Conway) | Jah-Maine Martin | RB | 2022 | 35987 |
| Crestwood (Sumter) | Ty'Son Williams | RB | 2020 | 17415 |
| Crestwood (Sumter) | Donald Rutledge | DB | 2020 | 29661 |
| Cross (Cross0 | Rod Wilson | DB | 2005 | 25922 |
| Daniel (Central) | DeAndre Hopkins | WR | 2013 | 354 |
| Daniel (Central) | Larry Craig | RB | 1939 | 4579 |
| Daniel (Central) | Shaq Lawson | DL | 2016 | 5780 |
| Daniel (Central) | Jarvis Jenkins | DL | 2011 | 9655 |
| Daniel (Central) | DeShawn Williams | DL | 2015 | 13363 |
| Daniel (Central) | Kent Lawrence | WR | 1969 | 17560 |
| Daniel (Central) | Garry Peters | DB | 2015 | 19980 |
| Daniel (Central) | Kevin Breedlove | OL | 2003 | 33845 |
| Daniels (Central) | Antwon Black | WR | 2001 | 39359 |
| Darlington (Darlington) | Ray Early | P | 2015 | 32812 |
| Davie County (Mocksville) | Chris Reynolds | QB | 2023 | 20820 |
| Denmark-Olar (Denmark) | Henry Odom (KR) | KR | 1983 | 14477 |
| Denmark-Olar (Denmark) | Henry Odom | RB | 1983 | 19226 |
| Dillon (Dillon) | Larry McClain | DL | 1981 | 15212 |
| Dillon (Dillon) | John Alford | DL | 1981 | 22968 |
| Dillon (Dillon) | Melvin Paige | OL | 2002 | 30716 |
| Dorman (Roebuck) | Adam Humphries | WR | 2015 | 4808 |
| Dorman (Roebuck) | Adam Humphries (PR) | PR | 2015 | 9535 |
| Dorman (Roebuck) | Ryan Sims | DL | 2002 | 11254 |
| Dorman (Roebuck) | Charone Peake | WR | 2016 | 20235 |
| Dorman (Roebuck) | JJ Arcega-Whiteside | WR | 2019 | 21287 |
| Dorman (Roebuck) | Vance Hammond | OL | 1991 | 25829 |
| Dorman (Roebuck) | Terry Wilburn | RB | 1996 | 27131 |
| Dorman (Roebuck) | Jordan McFadden | OL | 2023 | 33974 |
| Dorman (Roebuck) | Hart Turner | TE | 2004 | 34216 |
| Dreher (Columbia) | Gerald Perry | OL | 1988 | 7750 |
| Dreher (Columbia) | Ed Holler (P) | P | 1963 | 12035 |
| Dreher (Columbia) | Joel Wells (PR) | PR | 1957 | 14370 |
| Dreher (Columbia) | Ed Holler | LB | 1963 | 16214 |
| Dreher (Columbia) | Joel Wells | RB | 1957 | 21940 |
| Dreher (Columbia) | Corey Jenkins | LB | 2003 | 25256 |
| Dreher (Columbia) | Joel Wells (KR) | KR | 1957 | 34263 |
| Dutch Fork (Irmo) | Tyler Bass | K | 2020 | 5287 |
| Dutch Fork (Irmo) | Jalin Hyatt | WR | 2023 | 20917 |
| Dutch Fork (Irmo) | Matt Colburn | RB | 2019 | 28518 |
| Dutch Fork (Irmo) | Chad Geter | DL | 2017 | 29917 |
| Dutch Fork (Irmo) | Garrett Anderson | OL | 2010 | 31705 |
| Dutch Fork (Irmo) | Bryce Thompson | DB | 2021 | 33663 |
| Easley (Easley) | Stanley Morgan | WR | 1977 | 419 |
| Easley (Easley) | Stanley Morgan (PR) | PR | 1977 | 6953 |
| Easley (Easley) | Jay Hagood | OL | 1997 | 26649 |
| Eastside (Taylors) | Andre' Goodman | DB | 2002 | 6224 |
| Eastside (Taylors) | George Jones | RB | 1997 | 15889 |
| Eau Claire (Columbia) | Terry Long | OL | 1984 | 5591 |
| Eau Claire (Columbia) | Ricky Bell (DB) | DB | 1996 | 20899 |
| Eau Claire (Columbia) | Steve Williams (DE) | DL | 1972 | 22086 |
| Edmunds (Sumter) | Wayne Mass | OL | 1968 | 16547 |
| Fairfield Central (Winnsboro) | Orlando Ruff | LB | 1999 | 6597 |
| Fairfield Central (Winnsboro) | Tyler Thigpen | QB | 2007 | 14252 |
| Flora (Forest Acres) | Joseph Charlton | P | 2020 | 13526 |
| Flora (Forest Acres) | Robert Brannon | DL | 1985 | 21906 |
| Flora (Forest Acres) | Celestin Haba | DL | 2023 | 32037 |
| Fort Dorchester (North Charleston) | Robert Quinn | DL | 2011 | 1007 |
| Fort Dorchester (North Charleston) | Carlos Dunlap | DL | 2010 | 1236 |
| Fort Dorchester (North Charleston) | John Simpson | OL | 2020 | 13431 |
| Fort Dorchester (North Charleston) | Byron Maxwell | DB | 2011 | 13887 |
| Fort Johnson (Charleston) | Chuck Slaughter | OL | 1982 | 26249 |
| Fort Mill (Fort Mill) | Vance Walker | DL | 2009 | 9879 |
| Fort Mill (Fort Mill) | Daddy Potts | OL | 1926 | 13697 |
| Furman (Sumter) | Reggie Pleasant | DB | 1985 | 18658 |
| Gaffney (Gaffney) | Sidney Rice | WR | 2007 | 4457 |
| Gaffney (Gaffney) | Rocky McIntosh | LB | 2006 | 4531 |
| Gaffney (Gaffney) | Lou Sossamon | OL | 1946 | 7543 |
| Gaffney (Gaffney) | Zip Hanna | OL | 1945 | 10898 |
| Gaffney (Gaffney) | Denzelle Good | OL | 2015 | 20594 |
| Gaffney (Gaffney) | Dominique Stevenson | LB | 2002 | 25689 |
| Gaffney (Gaffney) | Joe Craig (PR) | PR | 2015 | 35088 |
| Gaffney (Gaffney) | Joe Craig (KR) | KR | 2015 | 36851 |
| Gaffney (Gaffney) | Joe Craig | WR | 2015 | 37222 |
| Gallman (Newberry) | Richard Sligh | DL | 1967 | 21921 |
| Garrett (North Charleston) | Mike Grant | LB | 1984 | 20155 |
| Garrett Academy Tech (North Charleston) | Trevon Sanders | DL | 2019 | 36517 |
| Georgetown (Georgetown) | Nate S. Allen | DB | 1971 | 6958 |
| Georgetown (Georgetown) | Patrick Bradford | DL | 2000 | 33089 |
| Goose Creek (Goose Creek) | Brandon Shell | OL | 2016 | 9642 |
| Goose Creek (Goose Creek) | Javon Kinlaw | DL | 2020 | 15482 |
| Gray Court-Owings (Gray Court) | Robert Patton | OL | 1952 | 15424 |
| Great Falls (Great Falls) | Banks McFadden | RB | 1940 | 8211 |
| Greenville (Greenville) | David Jones | DB | 2007 | 23341 |
| Greenville (Greenville) | William Henry | OL | 2004 | 34780 |
| Greenwood (Greenwood) | Ben Coates | TE | 1991 | 385 |
| Greenwood (Greenwood) | Josh Norman | DB | 2012 | 3522 |
| Greenwood (Greenwood) | Robert Brooks | WR | 1992 | 3876 |
| Greenwood (Greenwood) | D.J. Swearinger | DB | 2013 | 7489 |
| Greenwood (Greenwood) | Robert Brooks (PR) | PR | 1992 | 9376 |
| Greenwood (Greenwood) | Robert Brooks (KR) | KR | 1992 | 10963 |
| Greenwood (Greenwood) | Armanti Edwards | WR | 2010 | 18655 |
| Greenwood (Greenwood) | Ernest Dye | OL | 1993 | 20721 |
| Greenwood (Greenwood) | John Terry | OL | 1992 | 21622 |
| Greenwood (Greenwood) | Armanti Edwards (PR) | PR | 2010 | 24599 |
| Greenwood (Greenwood) | Larry Ryans | WR | 1993 | 28554 |
| Greenwood (Greenwood) | Larry Ryans (PR) | PR | 1993 | 31234 |
| Greenwood (Greenwood) | Larry Ryans (KR) | KR | 1993 | 32049 |
| Greenwood (Greenwood) | Sam Montgomery | DL | 2013 | 37885 |
| Greer (Greer) | Troy Pride | DB | 2020 | 26398 |
| Hanahan (Hanahan) | Herb Spencer | LB | 1987 | 9574 |
| Hanahan (Hanahan) | Marcus Howard | DL | 2008 | 20996 |
| Hanna (Anderson) | Martavis Bryant | WR | 2014 | 11142 |
| Hanna (Anderson) | Zacch Pickens | DL | 2023 | 26029 |
| Hanna (Anderson) | Preston Jones | QB | 1993 | 27312 |
| Hanna (Anderson) | Dan Palmer | OL | 1997 | 30834 |
| Hartsville (Hartsville) | Albert Haynesworth | DL | 2002 | 2643 |
| Hartsville (Hartsville) | Craig Thompson | TE | 1992 | 12449 |
| Hartsville (Hartsville) | Kelvin Moses | LB | 2000 | 22982 |
| Hartsville (Hartsville) | Lee Wiggins | DB | 1998 | 30674 |
| Hartsville (Hartsville) | Randy Wheeler | OL | 1997 | 30847 |
| Hartsville (Hartsville) | Tiyon Evans | RB | 2023 | 37112 |
| Heathwood Hall (Columbia) | Selvesta Miller | DL | 1999 | 29266 |
| Hilda (Blackville) | Troy Brown | WR | 1993 | 2311 |
| Hilda (Blackville) | Troy Brown (PR) | PR | 1993 | 3301 |
| Hilda (Blackville) | Joe Thomas (LB) | LB | 2014 | 9255 |
| Hilda (Blackville) | Troy Brown (KR) | KR | 1993 | 12641 |
| Hillcrest (Simpsonville) | Henry Marshall | WR | 1976 | 1531 |
| Hillcrest (Simpsonville) | Travelle Wharton | OL | 2004 | 5406 |
| Hillcrest (Simpsonville) | Mike Rose | DL | 2016 | 19967 |
| Hillcrest (Simpsonville) | Jamon Meredith | OL | 2009 | 20414 |
| Hillcrest (Simpsonville) | Al Whiting | WR | 1991 | 36423 |
| Hilton Head (Hilton Head) | Wayne Simmons | LB | 1993 | 6050 |
| Hilton Head (Hilton Head) | Poona Ford | DL | 2018 | 6522 |
| Hilton Head (Hilton Head) | Eddie Cohen | WR | 2008 | 34771 |
| Howard (Georgetown) | Mack Alston | TE | 1970 | 3423 |
| Howard (Georgetown) | Eric Allen (RB) | RB | 1972 | 24800 |
| Howard (Georgetown) | Eric Allen (KR) | KR | 1972 | 30593 |
| Indian Land (Indian Land) | Dorian Williams | LB | 2023 | 18258 |
| Irmo (Columbia) | Marion Reeves | DB | 1974 | 26926 |
| Irmo (Irmo) | Zafir Kelly | DB | 2022 | 38125 |
| Jackson (Kershaw) | Darrell Shropshire | DL | 2005 | 26860 |
| James Island (Charleston) | Roddy White | WR | 2005 | 423 |
| James Island (Charleston) | Langston Moore | DL | 2004 | 21532 |
| Jasper (Hardeeville) | Jovon Bush | DL | 2002 | 32941 |
| Johnson (Columbia) | Mike D. Jones | DL | 1991 | 5193 |
| Johnsonville (Johnsonville) | Jim Maxwell | LB | 2004 | 23569 |
| Jones (Sanford) | Steve Jones | RB | 1973 | 6971 |
| Jonesville (Jonesville) | Jim Youngblood | LB | 1973 | 1745 |
| Keenan (Columbia) | Tony McDaniel | DL | 2006 | 7328 |
| Keenan (Columbia) | Jarvis Borum | OL | 2001 | 28939 |
| Keenan (Columbia) | Chauncy Haney | LB | 2020 | 37790 |
| Keenan (Columbia) | David Young | DB | 2003 | 38429 |
| Kingstree (Kingstree) | Woody Myers | OL | 1988 | 30959 |
| Lake City (Lake City) | Derrick Faison | WR | 1990 | 20629 |
| Lake City (Lake City) | Damonte McKenzie | DL | 2000 | 29402 |
| Lake Marion (Santee) | Mike Williams (1994) | WR | 2017 | 3273 |
| Lake View (Lake View) | Shaquille Leonard | LB | 2018 | 541 |
| Lake View (Lake View) | Dewey Proctor | RB | 1943 | 18186 |
| Lake View (Lake View) | Anthony Waters | LB | 2008 | 27127 |
| Lamar (Lamar) | John Abraham | DL | 2000 | 346 |
| Lamar (Lamar) | Levon Kirkland | LB | 1992 | 1377 |
| Lamar (Lamar) | B.J. Goodson | LB | 2016 | 12347 |
| Lamar (Lamar) | Cobie Durant | DB | 2022 | 19925 |
| Lamar (Lamar) | Marshall McFadden | LB | 2011 | 29795 |
| Lamar (Lamar) | Michael Hamlin | DB | 2009 | 32340 |
| Lancaster (Lancaster) | Tom Addison | LB | 1960 | 1347 |
| Lancaster (Lancaster) | Markees Watts | LB | 2023 | 27837 |
| Latta (Latta) | Tyreik McAllister | WR | 2022 | 33181 |
| Latta (Latta) | Tyreik McAllister (KR) | KR | 2022 | 34077 |
| Latta (Latta) | Tyreik McAllister (PR) | PR | 2022 | 35499 |
| Laurens (Laurens) | Norris Brown | TE | 1983 | 17829 |
| Laurens (Laurens) | Rickey Foggie | QB | 1988 | 19367 |
| Laurens (Laurens) | Stacy Evans | DL | 1996 | 28728 |
| Laurens (Laurens) | Fred Foggie | DB | 1992 | 31216 |
| Lewisville (Richburg) | Sheldon Brown | DB | 2002 | 3138 |
| Lewisville (Richburg) | Mike Barber (LB) | LB | 1995 | 15132 |
| Lewisville (Richburg) | William Strong | DB | 1995 | 36469 |
| Lexington (Lexington) | Homer Hobbs | OL | 1949 | 15757 |
| Lexington (Lexington) | Demetris Summers | RB | 2006 | 28263 |
| Lexington (Lexington) | Demetris Summers (KR) | KR | 2006 | 32302 |
| Lincoln (McClellanville) | Perry Smith | DB | 1973 | 7316 |
| Lincoln (McClellanville) | Paul Williams (1947) | DB | 1969 | 18391 |
| Lincoln (McClellanville) | Paul Williams (PR) | PR | 1969 | 26187 |
| Lincoln (McClellanville) | Paul Williams (KR) | KR | 1969 | 26497 |
| Lippen (Columbia) | Samkon Gado | RB | 2005 | 14301 |
| Lockhart (Lockhart) | Mickey Sims | DL | 1977 | 11821 |
| Loris (Loris) | Jake McCullough | DL | 1989 | 27903 |
| Lower Richland (Hopkins) | Richard Seymour | DL | 2001 | 153 |
| Lower Richland (Hopkins) | Jonathan Goodwin | OL | 2002 | 2714 |
| Lower Richland (Hopkins) | David Patten | WR | 1997 | 3441 |
| Lower Richland (Hopkins) | Ernie Jackson | DB | 1972 | 5267 |
| Lower Richland (Hopkins) | Sanders Shiver | LB | 1976 | 5417 |
| Lower Richland (Hopkins) | David Patten (KR) | KR | 1997 | 9381 |
| Lower Richland (Hopkins) | Lance Laury | LB | 2006 | 18607 |
| Lower Richland (Hopkins) | Brandon Jamison | LB | 2006 | 27041 |
| Macedonia (Moncks Corner) | Pierson Prioleau | DB | 1999 | 9292 |
| Macedonia (Moncks Corner) | Courtney Brown | DL | 2000 | 9782 |
| Macedonia (Moncks Corner) | Joe Hamilton | QB | 2000 | 27910 |
| Macedonia (Moncks Corner) | Harvey Middleton | WR | 1998 | 38998 |
| Manning (Manning) | Fred Bennett | DB | 2007 | 16048 |
| Marion (Marion) | Louis Cooper | LB | 1985 | 9354 |
| Marion (Marion) | Tito Hannah | DL | 2000 | 29105 |
| Marlboro County (Bennettsville) | Robert Ayers | DL | 2009 | 5990 |
| Marlboro County (Bennettsville) | Anthony Cook | DL | 1995 | 11088 |
| Marlboro County (Bennettsville) | Brian Bratton | WR | 2005 | 19961 |
| Marlboro County (Bennettsville) | Quinton Teal | DB | 2007 | 25376 |
| Marlboro County (Bennettsville) | Rendrick Taylor | RB | 2010 | 26418 |
| Marlboro County (Bennettsville) | Brian Bratton (KR) | KR | 2005 | 28737 |
| Marlboro County (Bennettsville) | Mitchell Galloway | WR | 1997 | 29730 |
| Marlboro County (Bennettsville) | Brian Bratton (PR) | PR | 2005 | 34315 |
| Marlboro County (Bennettsville) | Mitchell Galloway (KR) | KR | 1997 | 34341 |
| Marlboro County (Bennettsville) | Ronheen Bingham | LB | 2019 | 34745 |
| Marlboro County (Bennettsville) | Noah Henderson | OL | 2023 | 37987 |
| Marlboro County (Bennettsville) | Cam Newton (DB) | DB | 2005 | 38424 |
| Mauldin (Mauldin) | Andru Phillips | DB | 2024 | 15919 |
| Mayesville (Mayesville) | Archie Reese | DL | 1978 | 5539 |
| McClenaghan (Florence) | Harry Carson | LB | 1976 | 281 |
| McCormick (McCormick) | Ron Lamb | RB | 1966 | 11580 |
| McCormick (McCormick) | Mataeo Durant | RB | 2022 | 34582 |
| Meggett (Charleston) | Walt Mitchell | DL | 1969 | 31067 |
| Miami (Greenville) | Dextor Clinkscale | DB | 1980 | 8194 |
| Middleton (Charleston) | Thomas Washington | DL | 2000 | 32956 |
| Mullins (Mullins) | Bishop Strickland | RB | 1951 | 13270 |
| Mullins (Mullins) | Xavier Legette | WR | 2024 | 15519 |
| Myrtle Beach (Myrtle Beach) | Robert Abraham | LB | 1982 | 7594 |
| Myrtle Beach (Myrtle Beach) | Lester Brown | RB | 1980 | 17704 |
| Myrtle Beach (Myrtle Beach) | Butchie Wallace | RB | 2006 | 29465 |
| Myrtle Beach (Myrtle Beach) | Lester Brown (KR) | KR | 1980 | 31500 |
| Newberry (Newberry) | Willie Scott | TE | 1981 | 4992 |
| Newberry (Newberry) | Greg Hartle | LB | 1974 | 16403 |
| Newberry (Newberry) | Mitchell Price (DL) | DL | 1983 | 19842 |
| Newberry (Newberry) | Cecil Caldwell | DL | 2001 | 30280 |
| Ninety Six (Greenwood) | Ron Williams | RB | 1993 | 17647 |
| Ninety Six (Greenwood) | Ron Williams (KR) | KR | 1993 | 37151 |
| North (North) | Chartric Darby | DL | 1998 | 7563 |
| North (North) | Freddie Martino | WR | 2014 | 24591 |
| North Augusta (North Augusta) | Charlie Waters | DB | 1970 | 1175 |
| North Augusta (North Augusta) | Craig Baynham | RB | 1967 | 9315 |
| North Augusta (North Augusta) | Matt Campbell | OL | 1994 | 10035 |
| North Augusta (North Augusta) | Craig Baynham (KR) | KR | 1967 | 12816 |
| North Augusta (North Augusta) | Fred Vinson | DB | 1999 | 24841 |
| North Augusta (North Augusta) | Grant Baynham | TE | 1997 | 32263 |
| North Augusta (North Augusta) | Parker Collins | OL | 2019 | 34951 |
| North Central (Kershaw) | Tyronne Drakeford | DB | 1994 | 9060 |
| North Central (Kershaw) | Corey Jackson | DL | 2003 | 28578 |
| North Charleston (North Charleston) | Bob Hudson | DB | 1951 | 2219 |
| North Charleston (North Charleston) | Bob Hudson (KR) | KR | 1951 | 14097 |
| North Charleston (North Charleston) | Bill Hudson | DL | 1957 | 15246 |
| North Charleston (North Charleston) | Corey Washington | WR | 2014 | 22335 |
| North Charleston (North Charleston) | Jarriel King | OL | 2011 | 28451 |
| North Myrtle Beach (Little River) | Ryan Quigley | P | 2012 | 7520 |
| North Myrtle Beach (Little River) | Temarrick Hemingway | TE | 2016 | 28888 |
| Northwestern (Rock Hill) | Johnathan Joseph | DB | 2006 | 1642 |
| Northwestern (Rock Hill) | Cordarrelle Patterson (KR) | KR | 2013 | 1771 |
| Northwestern (Rock Hill) | Ben Watson | TE | 2004 | 1822 |
| Northwestern (Rock Hill) | Cordarrelle Patterson | WR | 2013 | 3334 |
| Northwestern (Rock Hill) | Jeff Burris | DB | 1994 | 4831 |
| Northwestern (Rock Hill) | Rick Sanford | DB | 1979 | 5657 |
| Northwestern (Rock Hill) | Mason Rudolph | QB | 2018 | 6689 |
| Northwestern (Rock Hill) | Jeff Burris (PR) | PR | 1994 | 7231 |
| Northwestern (Rock Hill) | Derek Ross (KR) | KR | 2002 | 15269 |
| Northwestern (Rock Hill) | Derek Ross | DB | 2002 | 25914 |
| Northwestern (Rock Hill) | Jamie Robinson | DB | 2013 | 29434 |
| Northwestern (Rock Hill) | Caliph Brice | LB | 2022 | 38160 |
| Orangeburg-Wilkinson (Orangeburg) | Donnie Abraham | DB | 1996 | 2347 |
| Orangeburg-Wilkinson (Orangeburg) | Tim Jennings | DB | 2006 | 2579 |
| Orangeburg-Wilkinson (Orangeburg) | Max Runager | P | 1979 | 3612 |
| Orangeburg-Wilkinson (Orangeburg) | Dwayne Harper | DB | 1988 | 3631 |
| Orangeburg-Wilkinson (Orangeburg) | Arturo Freeman | DB | 2000 | 17002 |
| Orangeburg-Wilkinson (Orangeburg) | Maurice Kelly | DB | 1994 | 18530 |
| Orangeburg-Wilkinson (Orangeburg) | Woody Dantzler (KR) | KR | 2002 | 23019 |
| Orangeburg-Wilkinson (Orangeburg) | Jim Summers | DB | 1967 | 23806 |
| Orangeburg-Wilkinson (Orangeburg) | Deveron Harper | DB | 2000 | 25794 |
| Orangeburg-Wilkinson (Orangeburg) | Jonas Seawright | DL | 2005 | 26036 |
| Orangeburg-Wilkinson (Orangeburg) | Albert Huggins | DL | 2019 | 28062 |
| Orangeburg-Wilkinson (Orangeburg) | Woody Dantzler | RB | 2002 | 33960 |
| Parker (Spartanburg) | Connie Mack Berry | E | 1939 | 5534 |
| Pelion (Pelion) | Dalton Freeman | OL | 2014 | 27701 |
| Pendleton (Pendleton) | Tony Plantin | DL | 1998 | 29650 |
| Pickens (Pickens) | Rudy Hayes | LB | 1959 | 9394 |
| Pickens (Pickens) | Harold Alexander | P | 1993 | 11642 |
| Pickens (Pickens) | Rick Anthony | OL | 1974 | 28372 |
| Porter-Gaud (Charleston) | Ovie Mughelli | RB | 2003 | 4924 |
| Richland Northeast (Columbia) | T.J. Brunson | LB | 2020 | 31387 |
| Richland Northeast (Columbia) | Airese Currie | WR | 2005 | 35005 |
| Richlands Northeast (Columbia) | Johnny Maxey | DL | 2016 | 37612 |
| Ridge View (Columbia) | Brian Quick | WR | 2012 | 7905 |
| Ridge View (Columbia) | Dennis Daley | OL | 2019 | 18787 |
| Ridge View (Columbia) | Darell Scott | DL | 2009 | 24744 |
| Ridge View (Columbia) | Nasir Player | DL | 2020 | 35240 |
| Riverside (Greer) | Brandon Bennett | RB | 1998 | 5756 |
| Riverside (Greer) | Brandon Bennett (KR) | KR | 1998 | 10706 |
| Riverside (Greer) | Tremayne Stephens | RB | 1998 | 13975 |
| Riverside (Greer) | Tremayne Stephens (KR) | KR | 1998 | 14037 |
| Riverside (Greer) | Jon Kirksey | DL | 1993 | 21537 |
| Riverside (Greer) | Kevin Dodd | LB | 2016 | 28507 |
| Roberts (Holly Hill) | Adrian Dingle | DL | 1999 | 15351 |
| Roberts (Holly Hill) | Robert Evans | WR | 1975 | 31461 |
| Rock Hill (Rock Hill) | Chris Hope | DB | 2002 | 2045 |
| Rock Hill (Rock Hill) | Gerald Dixon | LB | 1993 | 4511 |
| Rock Hill (Rock Hill) | Phillip Adams (PR) | PR | 2010 | 16058 |
| Rock Hill (Rock Hill) | Phillip Adams | DB | 2010 | 20309 |
| Rock Hill (Rock Hill) | Ko Simpson | DB | 2006 | 20468 |
| Rock Hill (Rock Hill) | Jonathan Hefney | DB | 2008 | 21947 |
| Rock Hill (Rock Hill) | Arkee Whitlock | RB | 2007 | 27091 |
| Rock Hill (Rock Hill) | Tony Watkins | DB | 1995 | 28432 |
| Rock Hill (Rock Hill) | Jonathan Meeks | DB | 2013 | 32106 |
| Rock Hill (Rock Hill) | Arkee Whitlock (KR) | KR | 2007 | 33833 |
| Rock Hill (Rock Hill) | Jonathan Meeks | DB | 2013 | 38407 |
| Saluda (Saluda) | Jon Brooks | LB | 1979 | 15791 |
| Schofield (Aiken) | Barney Chavous | DL | 1973 | 2120 |
| Scott's Branch (Summerton) | Jerell Adams | TE | 2016 | 18703 |
| Seneca (Seneca) | Jimmy Orr | WR | 1958 | 622 |
| Seneca (Seneca) | Bennie Cunningham | TE | 1976 | 2627 |
| Seneca (Seneca) | Clarence Kay | TE | 1984 | 2997 |
| Seneca (Seneca) | Jimmy Orr (P) | P | 1958 | 12309 |
| Seneca (Seneca) | Hollis Hall | DB | 1982 | 19391 |
| Seneca (Seneca) | Dennis Hughes | TE | 1970 | 20902 |
| Seneca (Seneca) | Lemual Ligon | DB | 1999 | 28805 |
| Silver Bluff (Aiken) | Demarcus Lawrence | DL | 2014 | 1016 |
| Silver Bluff (Aiken) | Corey Chavous | DB | 1998 | 2896 |
| Silver Bluff (Aiken) | D'Wayne Bates | WR | 1999 | 10465 |
| Silver Bluff (Aiken) | Troy Williamson | WR | 2005 | 11819 |
| Silver Bluff (Aiken) | Troy Williamson (KR) | KR | 2005 | 17033 |
| Silver Bluff (Aiken) | Tarron Jackson | DL | 2021 | 26957 |
| Silver Bluff (Aiken) | Cordrea Tankersley | DB | 2017 | 29313 |
| Socastee (Myrtle Beach) | Hunter Renfrow | WR | 2019 | 5012 |
| Socastee (Myrtle Beach) | Hunter Renfrow (PR) | PR | 2019 | 9899 |
| South Aiken (Aiken) | Michael Dean Perry | DL | 1988 | 313 |
| South Aiken (Aiken) | Dekoda Watson | LB | 2010 | 10650 |
| South Fort Myers (Fort Myers) | Sammy Watkins | WR | 2014 | 3287 |
| South Pointe (Rock Hill) | Stephon Gilmore | DB | 2012 | 902 |
| South Pointe (Rock Hill) | Jadeveon Clowney | LB | 2014 | 1045 |
| South Pointe (Rock Hill) | Nick McCloud | DB | 2021 | 22293 |
| South Pointe (Rock Hill) | Derion Kendrick | DB | 2022 | 24101 |
| South Pointe (Rock Hill) | DeVonte Holloman | LB | 2013 | 29829 |
| South Pointe (Rock Hill) | Anthony Johnson (WR) | WR | 2019 | 34274 |
| South Pointe (Rock Hill) | Montay Crockett | WR | 2017 | 37130 |
| Southside (Greenville) | Michael Hamilton | LB | 1997 | 22643 |
| Southside (Greenville) | Corey Atkins | LB | 2000 | 26459 |
| Spartanburg (Spartanburg) | Stephen Davis | RB | 1996 | 819 |
| Spartanburg (Spartanburg) | Pete Tinsley | OL | 1938 | 3419 |
| Spartanburg (Spartanburg) | Steve Fuller | QB | 1979 | 3780 |
| Spartanburg (Spartanburg) | Anthony Simmons | LB | 1998 | 5429 |
| Spartanburg (Spartanburg) | Sid Tinsley (P) | P | 1945 | 10816 |
| Spartanburg (Spartanburg) | Sid Tinsley | RB | 1945 | 16100 |
| Spartanburg (Spartanburg) | Landon Cohen | DL | 2008 | 22653 |
| Spartanburg (Spartanburg) | Joel Bell | OL | 2009 | 28556 |
| Spartanburg (Spartanburg) | Tavien Feaster | RB | 2020 | 32920 |
| Spring Valley (Columbia) | Peter Boulware | LB | 1997 | 920 |
| Spring Valley (Columbia) | Andre Roberts (KR) | KR | 2010 | 2294 |
| Spring Valley (Columbia) | Andre Roberts (PR) | PR | 2010 | 2873 |
| Spring Valley (Columbia) | Willie J. Williams | DB | 1993 | 3473 |
| Spring Valley (Columbia) | Andre Roberts | WR | 2010 | 5077 |
| Spring Valley (Columbia) | Lee Flowers | DB | 1995 | 6974 |
| Spring Valley (Columbia) | Michael Boulware | DB | 2004 | 14786 |
| Spring Valley (Columbia) | Tyrone Legette | DB | 1992 | 17216 |
| Spring Valley (Columbia) | Jamel Smith | LB | 2000 | 26375 |
| Spring Valley (Columbia) | Chad Bates | OL | 1997 | 28309 |
| Spring Valley (Columbia) | Channing Tindall | LB | 2022 | 28744 |
| Spring Valley (Columbia) | Christian Miller | LB | 2019 | 30642 |
| St. Andrews Parish (Charleston) | Isaac Hilton | DL | 2004 | 28799 |
| St. John's (Charleston) | James Robinson | DL | 1984 | 23882 |
| St. John's (Charleston) | LeRoy Robinson | OL | 1982 | 24614 |
| St. John's (Johns Island) | Edmond Robinson | LB | 2015 | 25962 |
| St. John's (John's Island) | Charlie Brown | WR | 1982 | 2254 |
| St. Matthews (St. Matthews) | Willie Holman | DL | 1968 | 7842 |
| St. Matthews (St. Matthews) | Keith Williams (1964) | RB | 1987 | 36727 |
| St. Stephen's (Pineville) | Kendell Mack | OL | 1999 | 29060 |
| St. Stephens (St. Stephens) | Lance LeGree | DL | 2001 | 14438 |
| Statford (Goose Creek) | Harold Green | RB | 1990 | 1966 |
| Sterling (Greenville) | Bill Thompson | DB | 1969 | 516 |
| Sterling (Greenville) | J.D. Smith (1932) | RB | 1956 | 745 |
| Sterling (Greenville) | Bill Thompson (PR) | PR | 1969 | 4121 |
| Sterling (Greenville) | J.D. Smith (1932) (KR) | KR | 1956 | 8015 |
| Sterling (Greenville) | Bill Thompson (KR) | KR | 1969 | 12681 |
| Sterling (Greenville) | R.C. Gamble | RB | 1968 | 18182 |
| Stratford (Goose Creek) | Jon Alston (OL) | OL | 2005 | 28906 |
| Summerville (Summerville) | A.J. Green | WR | 2011 | 518 |
| Summerville (Summerville) | Stanford Jennings | RB | 1984 | 4247 |
| Summerville (Summerville) | Keith Jennings | TE | 1989 | 5284 |
| Summerville (Summerville) | Jamar Nesbit | OL | 1999 | 6493 |
| Summerville (Summerville) | Stanford Jennings (KR) | KR | 1984 | 7573 |
| Summerville (Summerville) | Kevin D. Long | OL | 1998 | 14914 |
| Summerville (Summerville) | Mark Slawson | WR | 1981 | 17422 |
| Summerville (Summerville) | Fred Worthy | DL | 1983 | 20502 |
| Summerville (Summerville) | De'Angelo Henderson | RB | 2017 | 26881 |
| Summerville (Summerville) | Terence Brown | OL | 2012 | 31690 |
| Summerville (Summerville) | Ian Rafferty | OL | 1999 | 32778 |
| Summerville (Summerville) | Chase Page | DL | 2006 | 35424 |
| Sumter (Sumter) | Freddie Solomon | WR | 1975 | 1419 |
| Sumter (Sumter) | Terry Kinard | DB | 1983 | 1809 |
| Sumter (Sumter) | Freddie Solomon (PR) | PR | 1975 | 3320 |
| Sumter (Sumter) | Derrick Witherspoon (KR) | KR | 1995 | 9668 |
| Sumter (Sumter) | Pressley Harvin | P | 2021 | 12783 |
| Sumter (Sumter) | Freddie Solomon (KR) | KR | 1975 | 15809 |
| Sumter (Sumter) | Ricardo Colclough (KR) | KR | 2004 | 18150 |
| Sumter (Sumter) | Ricardo Colclough | DB | 2004 | 19309 |
| Sumter (Sumter) | Dexter W. Davis | DB | 1991 | 21307 |
| Sumter (Sumter) | Derrick Witherspoon | RB | 1995 | 21560 |
| Sumter (Sumter) | Cleveland Pinkney | DL | 2001 | 28839 |
| Sumter (Sumter) | Raymond Johnson | DL | 2021 | 30641 |
| Sumter (Sumter) | Ronnie Burgess | DB | 1985 | 31453 |
| Sumter (Sumter) | Wally Richardson | QB | 1997 | 31657 |
| Sumter (Sumter) | Jamacia Jackson | LB | 2007 | 32584 |
| Sumter (Sumter) | Eric Watts | DL | 2024 | 34843 |
| Sumter (Sumter) | Greg Walker | OL | 2004 | 35637 |
| Sumter (Sumter) | Mariel Cooper | DB | 2016 | 36520 |
| Swansea (Swansea) | Victor Riley | OL | 1998 | 6293 |
| Swansea (Swansea) | Kendell Brooks | DB | 2023 | 38329 |
| Thornwell Orphanage (Greer) | Tom Wham | DL | 1949 | 5797 |
| Thornwell School (Clinton) | Josh Moore | OL | 2001 | 32699 |
| Thurmond (Johnston) | Ira Hillary (PR) | PR | 1985 | 14346 |
| Thurmond (Johnston) | Ira Hillary | WR | 1985 | 17525 |
| Thurmond (Johnston) | Antonio Hamilton | DB | 2016 | 19955 |
| Thurmond (Johnston) | Walter Scott | DL | 1996 | 29182 |
| Timberland (St. Stephen) | Tracy White | LB | 2003 | 10635 |
| Timmonsville (Timmonsville) | Kelvin Morris | RB | 2006 | 32637 |
| Travelers Rest (Travelers Rest) | Will Ford | RB | 2010 | 25974 |
| Travelers Rest (Travelers Rest) | Will Ford (KR) | KR | 2010 | 33552 |
| Union County (Union) | Rhoten Shetley | RB | 1940 | 12750 |
| Union County (Union) | Darrell Austin | OL | 1974 | 16173 |
| Union County (Union) | Shi Smith (PR) | PR | 2021 | 19433 |
| Union County (Union) | Shi Smith | WR | 2021 | 21026 |
| Union County (Union) | Sebastian Savage | DB | 1993 | 32140 |
| Union County (Union) | DJ Humphries | WR | 2002 | 39138 |
| Wagener-Salley (Wagener) | Robert Tyler | TE | 1988 | 23711 |
| Waldo (Mount Pleasant, SC) | Dexter Coakley | LB | 1997 | 1056 |
| Walterboro (Walterboro) | Darwin Walker | DL | 2000 | 6434 |
| Wando (Mount Pleasant) | Travis Jervey | RB | 1995 | 10460 |
| Wando (Mount Pleasant) | Barry Richardson | OL | 2008 | 12758 |
| Wando (Mount Pleasant) | Marion Brown | WR | 1982 | 16628 |
| Wando (Mount Pleasant) | Kevin Brown (RB) | RB | 2022 | 25749 |
| Wando (Mount Pleasant) | Justin Skinner | K | 1998 | 34008 |
| Wando (Mount Pleasant) | Gimel President | LB | 2017 | 38052 |
| Ware Shoals (Ware Shoals) | Jerry Butler | WR | 1979 | 1930 |
| Washington (Columbia) | J.C. Caroline | DB | 1956 | 2005 |
| Washington (Columbia) | Al L. Young | WR | 1971 | 23098 |
| Washington (Greenville) | Willie Belton (PR) | PR | 1971 | 11445 |
| Washington (Greenville) | Willie Belton (KR) | KR | 1971 | 11927 |
| Washington (Greenville) | Willie Belton | RB | 1971 | 16159 |
| Washington (Greenville) | Roy Kirksey | OL | 1971 | 24487 |
| West (Florence) | Brandon Bostick | TE | 2012 | 18152 |
| West (Florence) | Malliciah Goodman | DL | 2013 | 23171 |
| West (Florence) | Nate Cochran | P | 1997 | 32836 |
| West Ashley (Charleston) | Brett Toth | OL | 2018 | 35593 |
| West Florence (Florence) | Joey Walters | WR | 1977 | 8616 |
| West Florence (Florence) | Joey Walters (PR) | PR | 1977 | 31091 |
| West-Oak (Westminster) | Andy Lee | P | 2004 | 1657 |
| Westside (Anderson) | Shaun Ellis | DL | 2000 | 1366 |
| Westside (Anderson) | George Webster | LB | 1967 | 2895 |
| Westside (Anderson) | Dave Webster | DB | 1960 | 6757 |
| Westside (Anderson) | Roy Eppes | DB | 1978 | 22441 |
| Westside (Anderson) | Wentford Gaines | DB | 1976 | 22700 |
| Westside (Anderson) | Nick Hampton | LB | 2023 | 29682 |
| Westwood (Blythewood) | Vyncint Smith | WR | 2018 | 22320 |
| Westwood (Blythewood) | Amare Barno | DL | 2022 | 24402 |
| Westwood (Blythewood) | Vyncint Smith (KR) | KR | 2018 | 25208 |
| Westwood (Blythewood) | Cam Smith | DB | 2023 | 37192 |
| Whale Branch (Seabrook) | Dee Delaney | DB | 2018 | 26409 |
| Whitmire (Whitmire) | Donnie Shell | DB | 1974 | 341 |
| Whittermore (Conway) | Willie Grate | TE | 1969 | 13014 |
| Wilkinson (Orangeburg) | Alex Barron | OL | 2005 | 8681 |
| Williston-Elko (Williston) | Rafael Bush | DB | 2010 | 14951 |
| Wilson (Florence) | Lawrence Timmons | LB | 2007 | 1092 |
| Wilson (Florence) | Justin Durant | LB | 2007 | 4400 |
| Wilson (Florence) | Darian Durant | QB | 2005 | 17883 |
| Wilson (Florence) | Clayton Holmes | DB | 1992 | 25630 |
| Wilson (Florence) | Justin Evans (OL) | OL | 2018 | 33172 |
| Winnsboro (Winnsboro) | Terence Mack | LB | 1987 | 30965 |
| Woodland (Dorchester) | Tye Hill | DB | 2006 | 26083 |
| Woodland (Dorchester) | Michael Barnett | DL | 2020 | 37556 |
| Woodruff (Woodruff) | Tony Rice | QB | 1990 | 29177 |
| Woodruff (Woodruff) | Marcellas Dial | DB | 2024 | 37548 |
| Wren (Piedmont) | D.J. Jones | DL | 2017 | 6954 |
| Wren (Piedmont) | Hardy Mitchell | DL | 1998 | 33445 |
| York (York) | Marty Markett | DB | 2013 | 33187 |
| York (York) | Beau Nunn | OL | 2018 | 36803 |
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